Abstract
Secondary spontaneous pneumothorax (SSP) occurs in the context of underlying pulmonary disease. Our objectives were to estimate the relationship between SSP and short term air pollution exposure with nitrogen dioxide (NO2), ozone (O3) and particulate matter with a diameter ≤ 10 μm (PM10). Patients with SSP were included between June 1, 2009 and May 31, 2013, in 14 Emergency Departments in France. In this case–crossover design study, PM10, NO2, and O3 data were collected hourly from monitoring stations. Quantitative values, fast increase in air pollutant concentration, and air quality threshold exceedance were retained. These assessments were calculated for each of the 4 days prior to the event (Lag 1–Lag 4) for all case and control period, and for the entire exposure period. A total of 135 patients with SSP were included, with a mean age of 55.56 (SD 18.54) years. For short term exposure of PM10, NO2 and O3, no differences were observed between case and control periods in terms of quantitative values of air pollutant exposure (P > 0.68), fast increase in concentration (P > 0.12) or air quality threshold exceedance (P > 0.68). An association between O3 exposures cannot be ruled out, especially when considering the Lag 2 prior to the event and in warm seasons.
Highlights
Secondary spontaneous pneumothorax (SSP) occurs in the context of underlying pulmonary disease
We demonstrated a lack of connection between primary spontaneous pneumothorax (PSP) and N O2 and P M10 exposure, but could not rule out an association between O 3 exposure and PSP11
The exposure period corresponded as all case and control periods for each subject
Summary
Secondary spontaneous pneumothorax (SSP) occurs in the context of underlying pulmonary disease. Quantitative values, fast increase in air pollutant concentration, and air quality threshold exceedance were retained These assessments were calculated for each of the 4 days prior to the event (Lag 1–Lag 4) for all case and control period, and for the entire exposure period. For short term exposure of PM10, NO2 and O3, no differences were observed between case and control periods in terms of quantitative values of air pollutant exposure (P > 0.68), fast increase in concentration (P > 0.12) or air quality threshold exceedance (P > 0.68). The objectives of this study were: (1) to estimate the relationships between SSP and short term air pollution exposure with P M10, NO2 and O3; and (2) to investigate a time lag effect between exposure and the occurrence of SPP
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
