Abstract
A prospective randomized study of short-term vs long-term antiepileptic drug (AED) treatment of 206 subjects with new onset seizures and solitary cerebral cysticercus granuloma (SCCG) was conducted at the Department of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
Highlights
A prospective randomized study of short-term vs long-term antiepileptic drug (AED) treatment of 206 subjects with new onset seizures and solitary cerebral cysticercus granuloma (SCCG) was conducted at the Department of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
Carbamazepine and phenytoin were used as first-line AEDs
Complete spontaneous resolution of the SCCG had occurred in 66.3% of group A patients and in 57.4% of group B, while the remaining patients showed punctated residual calcification on CT
Summary
A prospective randomized study of short-term vs long-term antiepileptic drug (AED) treatment of 206 subjects with new onset seizures and solitary cerebral cysticercus granuloma (SCCG) was conducted at the Department of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India. Group A (98) patients were treated for 6 months and group B (108 patients) for 2 years. Patients were monitored during and 18 months or longer after tapering for 6 weeks and stopping treatment. Seizures were partial with or without secondary generalization in 80% of patients.
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