Abstract

Multiple episodes of polymorphic ventricular tachycardia (PVT), triggered by short-coupling (280–300ms) premature ventricular complexes (PVCs) showing a right bundle branch block (RBBB) pattern, occurred in a patient with Brugada syndrome. Isoproterenol infusion attenuated ST-segment elevation in leads V2–V3, but the triggered PVCs and PVT itself were not inhibited but rather increased. An implantable cardioverter-defibrillator (ICD) was introduced with a supplemental treatment of bepridil (150mg/d), which minimized his ST-segment elevation.

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