Short communication: Feeding a rumen-degradable amino acid affects plasma thyroxine and triiodothyronine concentrations

Abstract

Our previous published work demonstrated that feeding rumen-degradable valine to late-lactation dairy cows increased milk production compared with control-fed cows, with a response that was equivalent to that of recombinant bovine somatotropin. To further elucidate the response mechanism, we hypothesized that thyroxine (T4) and triiodothyronine (T3), which are important regulators of basal metabolism, may be involved. Previous short-term studies have demonstrated increased milk production when feeding iodinated casein. Eight multiparous Holstein dairy cows (255 ± 26.4 d in milk) were blocked by milk yield (34.1 ± 8.25 kg/d) and randomly assigned to 1 of 4 treatments using a replicated 4 × 4 Latin square design with 21-d periods (7 d for dietary adaptation and 14 d for data collection). Treatments were control (CON), a single injection of recombinant bovine somatotropin (rbST), and synthetic valine fed at 40 (V40) or 80 (V80) g/cow per day. Cows were fed a total mixed ration with a distillers dried grains carrier fed at 113.4 g/d containing no valine or added valine. Blood samples were collected twice during wk 2 and 3 of each period for T3 and T4 analysis. Concentrations of T4 (3.28, 3.90, 3.98, and 3.87 µg/dL for CON, rbST, V40, and V80, respectively) were increased for cows receiving rbST, V40, and V80 compared with CON cows. Concentrations of T3 (125.7, 140.7, 148.8, and 139.7 ng/dL) were increased for cows receiving rbST, V40, and V80 compared with CON cows, with cows receiving V40 having the highest T3 concentrations. In conclusion, feeding rumen-degradable valine increases plasma T4 and T3 concentrations, which would explain the mechanism leading to increased milk production.