Short Communication: Effect of pH on Absorption of Immunoglobulin G in Neonatal Calves

Abstract

We fed newborn calves (n=60) maternal colostrum (n=12) or a colostral supplement product derived from edible bovine serum (n=48). Sodium citrate was added to supplements to achieve a final pH of 7.5, 7.0, 6.0, and 5.0. Calves were fed colostrum (2 L/feeding) or supplement (454g reconstituted in 2L of water) at 1.2 and 12.6h of age, which provided a total of 156 (colostrum) or 90 (supplement) g of IgG. We sampled jugular blood at 0 and 24h of age to determine plasma IgG. Mean plasma IgG concentrations at 0 and 24h of age were 0 and 6.7g/L and were markedly higher in calves fed maternal colostrum compared with supplements (10.7 vs. 6.5g/L) and were higher in Jersey vs. Holstein calves (8.5 vs. 6.1g/L). Estimated apparent efficiency of IgG absorption was unaffected by treatment and averaged 20%. These data indicate that pH of colostral supplements between 7.5 and 5.0 do not markedly influence the efficiency of IgG absorption.