SHORT- AND LONG-TERM CLINICAL OUTCOMES IN PATIENTS UNDERGOING RESCUE PERCUTANEOUS CORONARY INTERVENTION COMPARED WITH PRIMARY PERCUTANEOUS CORONARY INTERVENTION IN ST-ELEVATION MYOCARDIAL INFARCTION

Abstract

Results: Significant baseline differences between the rescue PCI and PPCI groups included age (60.4 vs. 62.9, p=0.02), current smoking status (45.0% vs. 35.0%, p=0.01), ejection fraction (46.6% vs. 49.5%, p=0.03), STEMI-to-balloon-time (7.9 vs. 4.6 hours, [and door-to-balloon-time] both p<0.001), and Killip class IV (9.9% vs. 5.2%, p=0.02). Peri-procedural glycoprotein IIb/IIIa-inhibitor use was less in rescue patients (48.8% vs. 74.9%, p<0.001), but use of anti-thrombins or clopidogrel preloading was similar. The incidence of pre-PCI Thrombolysis in Myocardial Infarction (TIMI) 3 flow was higher among rescue (42.6% vs. 19.5%, p<0.0001) than PPCI patients, however, post-PCI TIMI 3 flow was similar in the two groups (89.1% vs. 91.5%, p=0.27). No significant differences were observed in any of the shortor long-term clinical endpoints between rescue PCIs and PPCIs including in-hospital bleeding complications (4.9% vs. 3.5%, p=0.34), 30-day mortality (6.2% vs. 6.0%, p=0.94), and overall major adverse cardiovascular events (MACE) (11.7% vs. 10.1%, p=0.52), and 12-month mortality (9.0% vs. 8.0%, p=0.67), and MACE (18.0% vs. 18.1%, p=0.99).