Abstract
survival and freedom from distant relapse were calculated using the Kaplan-Meier method. Results: The 5-year local control rate was 98%. Control of disease in the orbit was achieved in all but one patient who developed an outof-field recurrence after irradiation of a lacrimal tumor and was salvaged successfully with further radiation therapy. The 5-year regional control rate was 91% (3 patients failed in the contralateral orbit and 1 patient failed in the ipsilateral parotid). Freedom from metastasis, cause-specific survival, and overall survival rates at 5 years were 76%, 89%, and 76%, respectively. Acute toxicity was minimal. Eight patients (18%) reported worsened vision following radiation therapy, and cataracts developed in eight patients. Cataracts developed in 6 of 28 patients treated without lens shielding (21%) and 2 of 16 patients (13%) treated with lens shielding. No patient developed significant late lacrimal toxicity. Conclusion: Radiation therapy is a safe and effective local treatment in the management of orbital lymphoma. Author Disclosure: S. Kharod: None.M.P. Herman: None. C.G. Morris: None. J. Lightsey: None. W.M. Mendenhall: None. N.P. Mendenhall: None.
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