Shield effect of resistance jumping training on biomechanical parameters in gastrocnemius muscles of diabetic animals

Deniele Bezerra Lós,Suzy Kelly Ferreira Silvestre Da Silva,Rodrigues De Freitas,Waydja Lânia Virgínia De Araújo Marinho,Ana Cristina Falcão Esteves,Marcos Paulo Galdino Coutinho,Camilla Rodrigues De Souza Silva,Cybelle Da Silva Nery,Rafael Dornelas E Silva,Elvis Da Silva

doi:10.1186/1758-5996-7-s1-a12

Deniele Bezerra Lós, Suzy Kelly Ferreira Silvestre Da Silva + Show 8 more

Open Access

https://doi.org/10.1186/1758-5996-7-s1-a12

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Abstract

Background Chronic hyperglycemia resulting from diabetes mellitus undertakes several body cells through the formation of advanced glycation end products and activation of the polyol pathway (Brownlle, 2005), promoting reduction of electrical activity in skeletal muscle and the regenerative capacity of its cells, as well as impaired contractility and increased tissue stiffness. In turn, the amplify muscle work during exercise is able to elicit several essential biochemical reactions for hypertrophy, power gain and enhance muscle function (Andersen et al., 1996, 1997, 2004, 2005).

Highlights

Chronic hyperglycemia resulting from diabetes mellitus undertakes several body cells through the formation of advanced glycation end products and activation of the polyol pathway (Brownlle, 2005), promoting reduction of electrical activity in skeletal muscle and the regenerative capacity of its cells, as well as impaired contractility and increased tissue stiffness
gastrocnemius-plant complex demonstrated in diabetic animals (GDS) and GDT animals were administered with an intraperitoneal dose of streptozotocin to induce diabetes, which was confirmed by measurement of blood glucose fasting on the 3rd and 7th day post induction
GCT and GDT animals were submitted to an overload jumping exercise program of up to 50% body weight, 5 times a week during 9 weeks

Summary

Background

Chronic hyperglycemia resulting from diabetes mellitus undertakes several body cells through the formation of advanced glycation end products and activation of the polyol pathway (Brownlle, 2005), promoting reduction of electrical activity in skeletal muscle and the regenerative capacity of its cells, as well as impaired contractility and increased tissue stiffness. The amplify muscle work during exercise is able to elicit several essential biochemical reactions for hypertrophy, power gain and enhance muscle function (Andersen et al, 1996, 1997, 2004, 2005)

Materials and methods

Results

Conclusion