Shenfu injection in the pre-expansion perioperative treatment of acute hemorrhagic shock effect of observation

Abstract

Objective To observe the Senate anesthesia injection in the pre-expansion treatment of acute hemorrhagic shock patients and evaluate the results, explore the Shenfu injection in the pre-expansion used in the treatment of acute hemorrhagic shock perioperative treatment of the feasibility of And clinical significance.Methods Acute hemorrhagic shock patients were randomly divided into 50 cases of the observation group (I group, n = 25) and the control group (cn group, n = 25). Two groups of patients with general anesthesia endotra-cheal intubation later. Group I after the Narcotic give Shenfu injection 100ml in 5% glucose injection 500ml intravenous fluid therapy and pre-expansion (colloidal refers to the liquid molecular.weight hydroxyethyl starch 6% HES or Timor million); II group 5% Glucose and sodium chloride injection 500ml intravenous drip. Other blood transfusion, such as vasodilative anti-shock treatment 2, the same group. Monitoring 30,60,120 min after the injection of all time blood pressure, heart rate, cardiac output (CO) and volume changes in Group ￠n of the record amount of bleeding and blood transfusion volume. Compare the two groups were observed after injection of changes in arterial blood gases. Results ① I results of the Group Participation intravenous injection and pre-expansion treatment of liquid after 30, 60 min, blood pressure picked up, cardiac output (CO rebound), heart rate decreased significantly with the early II group (P < 0.05); in the urine 1 h And 2 h with the group II a very significant difference (P<0.05 orP<0.01).② Injection after 90 min ⒌￠n group of blood gas analysis and indicators increased II group were significantly different (P < 0.05 orP < 0.01 ). Conclusion Conclusions of the Senate anesthesia injection in the pre-expansion in the treatment of acute hemorrhagic shock, and rapid restoration of hemodynamic stability, improve microcirculation and metabolism of the organization to promote the recovery of shock, Perioperative to increase security in areas such as better Effect. Key words: Peri-operationai period; Shenfu injection; Hemorrhagic hypovolemic shock; Pre-expan-sion treatment