Shellfish polysaccharides: A comprehensive review of extraction, purification, structural characterization, and beneficial health effects

Abstract

Global food systems are currently facing great challenges, such as food sources, food safety, and environmental crises. Alternative nutritional resources have been proposed as part of the solution to meeting future global food demand. In the natural resources, shellfish are the major component of global aquatic animals. Although most studies focus on the allergy, toxin, and contamination of shellfish, it is also a delicious food to the human diet rich in proteins, polysaccharides, minerals, and omega-3. Among the functional ingredients, shellfish polysaccharides possess nutritional and medicinal values that arouse the great interest of researchers. The selection of the extraction approach and the experimental condition are the key factors that influence the extraction efficiency of shellfish polysaccharides. Importantly, the purification of crude polysaccharides comprises the enrichment of shellfish polysaccharides and isolation of fractions, also resulting in various structural characteristics and physicochemical properties. Chemical modification is also an efficient method to further improve the biological activities of shellfish polysaccharides. This review summarizes the extraction, purification, structural characterization, and chemical modification methods for shellfish polysaccharides. Additionally, the beneficial health effects of shellfish polysaccharides are highlighted, with an emphasis on their potential mechanism. Finally, current challenges and perspectives on shellfish polysaccharides are also spotlighted.