Abstract

Sheep scab is caused by the mite Psoroptes ovis and is the most important ectoparasitic disease of sheep in the UK. Sheep scab represents a significant threat to animal welfare, making a rapid and accurate diagnosis of paramount importance. Recently the Moredun Research Institute (MRI) has developed a diagnostic ELISA for the detection of antibodies specific to a mite allergen (Pso o 2) which has proven highly sensitive in the diagnosis of sub-clinical infestation. At the same time, worldwide interest has grown over the application of microfluidic paper-based analytical devices (µPADs) for low cost, point of care, multiplexed analyses. The combined application of these new technologies with the existing Pso o 2 antibody ELISA could represent a very powerful, improved diagnostic tool for sheep scab.

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