Sharpshooter (40%Profenofos and 4% Cypermethrin)-Induced Oxidative Stress Response in African Catfish Clarias Gariepinus

doi:10.34297/ajbsr.2020.07.001189

Abstract

Oxidative stress has been widely studied in experiments and well recognized as an important mechanism involving in aging and various diseases, such as cancers, cardiovascular diseases, and degenerative diseases. Based on the supportive findings of experimental research, many trials with clinically feasible therapy targeting for oxidative stress have been conducted. Even clinical evidence based on meta-analyses keeps mounting. The scope of this article is to review the mechanisms based on basic experiments and available evidence about the clinical application of oxidative stress-targeting therapeutic strategies. In addition, specific ways for patients undergoing maintenance hemodialysis, such as electrolyzed-reduced water (ERW) for dialysis water, are mentioned.

Highlights

Pesticide is any substance or mixture of substance used to prevent, destroy, or controlling pest which include vectors of human or animal diseases, unwanted plants or animals that cause harm or interfere with the agricultural processes [1]
The effect of the sub-lethal concentrations of 0.014, 0.036 and 0.00mg/L on the oxidative stress parameters for 1, 5, 10 and 15 days were determined in triplicate with sets of 10 fish based on the LC50 of sharpshooter at 96hours
The superoxide dismutase (SOD) value decreased with increase in concentration of sharpshooter compared with control (0.491±0.006b2 to 0.053±0.005b2).There was a significant decrease in the SOD activities at days 5 and 10 when the concentration of the pesticide increased to 0.036mg/L compared with the control

Summary

Introduction

Pesticide is any substance or mixture of substance used to prevent, destroy, or controlling pest which include vectors of human or animal diseases, unwanted plants or animals that cause harm or interfere with the agricultural processes [1]. Pollution of the aquatic environment is one of the major environmental threats in the world as it affects aquatic organism and even health of human being. Sharpshooter is a spectrum insecticide made up of 40% profenofos and 4% cypermethrin as active ingredients. It is used in treatments of ectoparasitic disease and pest of cotton, maize and vegetables [7]

Objectives

Methods

Results

Conclusion