Abstract

A 46-year-old man had recurrent episodes of diffuse hyperhidrosis and hypothermia (Video 1) lasting approximately 20 minutes for 20 days. His temperature was 35.4°C, blood pressure was 159/101 mm Hg, heart rate was 120/min, and diffuse hyperhidrosis was the only neurologic sign during an episode. Seizures were considered, but EEG during an episode was normal. MRI showed corpus callosum agenesis (Figure). He was diagnosed with Shapiro syndrome, which may be due to hypothalamic dysfunction and is responsive to clonidine and carbamazepine.1,2 Because of lack of clonidine and hyponatremia, the patient was treated with levetiracetam, and the episodes disappeared after 5 days.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.