Abstract

Bending rigidity of cellular membranes plays a key role in governing several cell remodeling processes such as endocytosis, exocytosis, cell division and viral uptake. Due to ease of implementation, fluctuation spectroscopy is a widely used tool to measure the shape fluctuations of giant unilamellar vesicles (GUVs) to determine membrane bending rigidity and compositional effects (see e.g. Faizi et al. Soft Matter 15:6006, 2019). in this approach, a time series of vesicle contour is recorded in the equatorial plane.

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