Sexual Function in Patients With Inflammatory Bowel Disease: Results of a Web-Based Health Survey

Abstract

Introduction: To assess sexual function and identify variables associated with sexual function in inflammatory bowel disease (IBD). Methods: A survey was developed incorporating demographic and clinical variables, the Manitoba index of disease activity, the body image questionnaire and the sexual function questionnaire (SFQ). Content validity and reliability were assessed. Eight hundred six patients with at least one office visit in the last 18 months were identified and mailed an invitation to complete the survey with accompanying web-link. Results: One hundred seventeen patients responded. Eighty-four percent were women, 64% were married or living with a partner, 88% had at least some college education, and 94% were heterosexual. Eightythree percent of respondents had Crohn’s disease and 48% reported active symptoms in the past month. Mean SFQ scores were 3.8±0.9 in men and 2.5±1.0 in women (p<0.001). Sexual function was higher in men than in women for all subscales except for relationship and problems. For men, SFQ scores were similar to historical controls; however SFQ scores in women were similar to historical controls with cancer (Table 1). Lower SFQ scores were associated with anxiety and distorted body image in women. Forty-three percent of women reported not being sexually active compared to 11% of men. Anxiety about sexual performance, lack of interest, vaginal dryness, and pain with intercourse were frequently reported problems in women (Table 2). Erectile problems were reported in ˜20% of men. Sixty-three percent of women reported that IBD had a negative impact on their sex life compared to 22% of men. Fifty-two percent, 54%, and 60% of women report decreased interest or desire, difficulty achieving an orgasm, and orgasms of decreased intensity respectively.Table 1: SFQ Scores for Men and Women With IBD Compared to Historical Cancer Patients and ControlsTable 2: Frequency of Sexual Problems Reported Greater Than 50% of the Time by WomenConclusion: Sexual function is decreased in women with IBD. Providers should consider screening for sexual function, referring patients with sexual problems for evaluation. Prospective studies are needed to assess sexual function over time, including the impact of medical treatment. This research was supported by an industry grant from Abbvie.