Abstract
Purpose: The prevalence and burden of osteoarthritis (OA) is higher in females than males. Although defects or alterations in the extracellular matrix (ECM) network can lead to chondrocyte damage and cartilage degeneration, no studies have focused on sexual dimorphism at the ECM level. Moreover, while controlling inflammation-induced catabolism in cartilage is crucial to prevent the extension of tissue damage, there is no data on sex differences in chondrocytes’ catabolic function. Therefore, we aim to investigate sex differences in the constituents of the ECM and in the chondrocyte anabolic and catabolic function.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
