Abstract
The prevalence of Human Immunodeficiency Virus (HIV) and Hepatitis B Virus (HBV) infections and their co-infection are rarely reported among undergraduate Nigerians. This study sought to provide data in the said direction and discuss policy imperatives.
Highlights
One major cause of mortality from liver disease world-wide is hepatitis B virus (HBV)
Human Immunodeficiency Virus (HIV)/AIDS is a serious public health issue globally, but in sub-Saharan Africa, where prevalence rates are as high as 25.8%
The National Agency for the Control of AIDS (NACA) in Nigeria reported a prevalence of 1.5 percent among adults in 2018 [6]
Summary
Their heights and weights were measured using standard protocol; and their body mass index (BMI) calculated. Peripheral venous blood samples (3 ml) were obtained from each subject and HIV antibodies were screened for using a national serial algorithm process, involving different rapid diagnostic test kits [Determine-HIV 1&2 (Alere Inc., Massachusetts), Uni-GoldTM Recombigen® HIV-1/2 (Trinity Biotech, Wicklow) and Stat-PakHIV-1&2 (Chembio Diagnostic Systems, Inc. Medford)]. On the same samples Hepatitis B surface antigen (HBsAg) rapid test, which is based on the principle of sandwich immunoassay for determination of the antigen in serum or plasma or whole blood, was used to screen for the presence of hepatitis B virus (HBV). All the rapid diagnostic kits used in this study have sensitivity and specificity values of > 95% according to their manufacturers. A significance threshold of P < 0.05 was adopted for all analyses
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