Sex-Specific Associations Between Bone-Loading Score and Adiposity Markers in Middle-Aged and Older Adults.

Abstract

The authors examined sex-specific relationships between fat mass index (FMI), android/gynoid (A/G) fat ratio, relative skeletal muscle mass index, and Bone-Specific Physical Activity Questionnaire derived bone-loading scores (BLSs) in middle-aged and older adults (men, n = 27; women, n = 33; age = 55-75years). The FMI, A/G fat ratio, and relative skeletal muscle mass index were estimated by dual-energy X-ray absorptiometry. The Bone-Specific Physical Activity Questionnaire was used to assess: (a)BLSpast (age 1 until 12months before the study visit), (b)BLScurrent (last 12months), and (c)BLStotal (average of [a] and [b]) scores. Separate multiple linear regression analysis of (a)age, FMI, and relative skeletal muscle mass index and (b)age, height, and A/G fat ratio versus BLS revealed that FMI and A/G fat ratio were negatively associated with BLSpast and BLStotal (p < .05) in women only. Adiposity and, specifically, central adiposity is negatively related to bone-loading physical activity in middle-aged and older women.