Abstract
Although the age-specific incidence and mortality of stroke is higher among men, stroke has a greater clinical effect on women. However, the sex differences in stroke among elderly patients are unknown. Therefore, we aimed to assess the sex differences in stroke among elderly stroke patients. Between 2005 and 2013, we recruited 1484 consecutive acute ischemic stroke (AIS) patients (≥75 years old) from a specialized neurology hospital in Tianjin, China. Information regarding their stroke subtypes, severity, risk factors, and outcomes at 3 and 12 months after stroke were recorded. Comparing with men, women had a significantly higher prevalence of severe stroke (17.20 vs. 12.54%), hypertension (76.42 vs. 66.39%), dyslipidemias (30.35 vs. 22.76%), and obesity (18.40 vs. 9.32%), P < 0.05. Comparing with women, men had a significantly higher prevalence of intracranial artery stenosis (23.11 vs. 17.45%), current smoking (29.60 vs. 13.05%), and alcohol consumption (12.15 vs. 0.47%), P < 0.05. Moreover, dependency was more common among women at 3 and 12 months after stroke, although the sex difference disappeared after adjusting for stroke subtypes, severity, and risk factors. Elderly women with AIS had more severe stroke status and worse outcomes at 3 and 12 months after stroke. Thus, elderly female post-AIS patients are a crucial population that should be assisted with controlling their risk factors for stroke and changing their lifestyle.
Highlights
The latest report indicates that stroke was the second most common cause of death and the third most common cause of reduced disability-adjusted life-years worldwide in 2010 (GBD 2013 Mortality and Causes of Death Collaborators, 2015)
A total of 6695 patients with first-ever acute ischemic stroke (AIS) were recruited during the study period, 1484 patients were included in this study after excluding 5211 patients aged
The median National Institute of Health stroke scale (NIHSS) and Bethel index (BI) on admission were higher for women than for men, the modified rank scale (mRS) was similar for both sexes
Summary
The latest report indicates that stroke was the second most common cause of death and the third most common cause of reduced disability-adjusted life-years worldwide in 2010 (GBD 2013 Mortality and Causes of Death Collaborators, 2015). The age-specific stroke incidence and mortality is higher among men, the total number of strokes is higher and the outcomes are worse among women, as women live longer and the risk of stroke increases with age (Niewada et al, 2005; Reeves et al, 2008). This difference will become increasingly significant in the coming decades. The age-specific incidence and mortality of stroke is higher among men, stroke has a greater clinical effect on women. We aimed to assess the sex differences in stroke among elderly stroke patients
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