Abstract

The high-density lipoprotein cholesterol and high-density lipoprotein subfraction (HDL 2 and HDL 3) concentrations were examined in 170 young black adults. The women examined had significantly higher total high-density lipoprotein cholesterol concentrations than the men, i.e., 57.0 mg/dl vs 51.2 mg/dl, P < 0.002. The increased high-density lipoprotein cholesterol among women represented a significant increase in both HDL 2 and HDL 3 cholesterol concentrations. The sex differential could not be explained by body mass index, alcohol consumption, or physical activity. The determinants of high-density lipoprotein cholesterol for men appeared to be different than those for women.

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