Abstract

THE INCREASING use of powdered red squill (Urginea maritima) as a specificraticide has led to considerable study concerning the nature of therat'killing principle that has not as yet been isolated in pure form (6). Inthese investigations many workers observed that the female rat was moresusceptible than the male to the powder or the extracts of red squill. Clare‘mont (i) in 1927 reported that the female rat was about twice as susceptibleto this toxic principle as was the male. Winton (2) in 1927 and LeBlanc (3)in 1938 confirmed the observations of Claremont.The present work was undertaken to determine the relationship of thesex hormones to the difference in response of the female and the male rat tored squill powder. EXPERIMENTAL Albino rats were fasted for 24 hours, weighed and fed powdered redsquill thoroughly mixed with dry bread crumbs and mineral oil

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