Abstract
1. Historical landmarks in studies of reproduction and sex determination 2. Mechanisms of sex determination 3. Differentiation of the gonads 4. Differentiation of the genital duct system 5. Anomalous sexual development in domestic species 6. Abnormal sexual development in laboratory rodents 7. Abnormal sexual development in man 8. Sexual differentiation in chimaeras 9. Asymmetries in the reproductive system and their significance 10. Concluding thoughts and a current perspective.
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