Abstract

Objective To contrast the remifentanil with sevofrane used in general anesthesia in laparoscopic cholecystectomy to patients' circulation function and side reactions when they woke up.Methods Seventy laparoscopic cholecystectomy patients were divided into remifentanil group and sevofrane group,and 35 patients each.Remifentanil group used remifentanil and propofol to maintain anesthesia,sevofrane group used low-flow sevofrane closed - circuit to maintain anesthesia,observed the patients' BP and HR deference before and after building pneumoperitoneum 5,10 min and before and after extubate trached cannula 5,10 min and also observed the patients' palinesthesia time,adverse reactions when extubate trached cannula,pain and perception in operation and the nausea and vomiting rate after operation.Results The patients'palinestheaia time,adverse reaction when extubate trached cannula,pain and perception in operation and the nausea and vomiting rate after operation between the two groups had no statistics deference.The patients' systolic pressure before and after building pneumoperitoneum 5,10 min in two groups remarkably declined,but the remifentanil group declined more.The HR in remifentanil group before and after building pneumoperitoneum 5,10 min all remarkably declined contrast to proanethesia(P<0.01).Conclusions Remifentanil and sevofrane all fit laparoscopic cholecystectomy,but sevofrane has less restraint to circulation and more safer. Key words: Remifentanil; Sevofrane; Low-flow; Laparoscopic; Circulation

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