Severity, Progress, and Related Factors of Mood Disorders in Patients with Coronary Artery Disease: A Retrospective Study.

Changbae Lee,Sang Cheol Lee,Ki Bum Won,Eun Jae Ko,Soe Hee Ann,Sangwoo Park,Yeon Seob Shin

doi:10.3390/healthcare8040568

Changbae Lee, Sang Cheol Lee + Show 5 more

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https://doi.org/10.3390/healthcare8040568

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Journal: Healthcare	Publication Date: Dec 16, 2020
Citations: 4	License type: CC BY 4.0

Affiliation: University of Ulsan, Ulsan University Hospital

Abstract

Patients with coronary artery disease (CAD) are more likely to experience depression and anxiety, which, in turn, are risk factors for CAD. The Beck depression inventory (BDI) and Beck anxiety inventory (BAI) were applied for mood evaluation during hospitalization and again 3 months after discharge in 118 patients with CAD, and cardiopulmonary exercise tests were conducted in the outpatient department. Of the patients diagnosed with CAD, 40 (33.9%) had depressive moods, and 51 (43.2%) had anxious moods. A family history of CAD, low Korean activity scale index (KASI), and use of beta-blockers were independent factors causing depressive mood, while lower left ventricular ejection fraction (LVEF) and low KASI score were independent factors causing anxious mood. A considerable number of patients (35.7% with depressive mood and 25.0% with anxious mood) still had emotional problems after 3 months of discharge. The change values of BDI were associated with lower LVEF and longer hospital stay, while those of BAI was associated with a longer hospital stay. Since some patients had depressive and anxious moods after three months of discharge, evaluating and treating them are essential.

Highlights

Coronary artery disease (CAD) is the global leading cause of death [1]
33 (28%), 32 (27.1%), and 53 (44.9%) patients were diagnosed with ST-elevation myocardial infarction (MI), non-ST-elevation MI, and unstable angina, respectively
None of the patients had been previously diagnosed with depression or anxiety, whereas 13 patients (11.0%) had family histories of coronary artery disease (CAD)

Summary

Introduction

Coronary artery disease (CAD) is the global leading cause of death [1]. In addition to traditional risk factors, such as male sex, smoking, and hyperlipidemia, which lead to a reduction in the coronary artery flow, depression and anxiety are risk factors associated with CAD [2,3,4,5,6,7]. The anxiety prevalence rate in patients with CAD is almost twice (36%) that of the general population in the United States [10]. Depression and anxiety in patients with CAD are associated with increased mortality, morbidity, and recurrence rate [11,12,13,14,15,16,17].

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