Severe Weight Gain With Long-Acting Injectable Risperidone

Abstract

To the Editor: Weight gain is a major problem with second-generation antipsychotics.1 Risperidone is generally considered to be of moderate risk in inducing weight gain when compared to other second-generation antipsychotics. We report the case of a patient diagnosed with schizophrenia, catatonic type, who gained 84 lb (38.1 kg) during 14 months of therapy with long-acting injectable risperidone.