Abstract
Objective: To measure 25-hydroxyvitamin D (25(OH)D) serum concentration among pregnant women in the first trimester and its association with first-trimester pregnancy loss in the Eastern Black Sea region of Turkiye. Methods: In this retrospective, cross-sectional study, we collected health records of pregnant women attending prenatal care at our department between March 2020 and December 2020. Serum 25 (OH)D levels were measured in the first trimester, and the patient's characteristics and the course of the pregnancy were analyzed. We investigated the association between maternal vitamin D deficiency and the risk of subsequent miscarriage. Results: The final analysis included 246 pregnant women, with 50 (20.3%) had a miscarriage in the first-timester. The prevalence of vitamin D deficiency was high in the group, with 78.5% of the study group having serum levels of 25(OH)D
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