Abstract

A 37-year old female with endodontitis received metronidazole 0.4 g three times daily and cefuroxime axetil 0.25 g twice daily according to the doctor′s advice. Three days after medication, the patient developed pain and ulcers on her oral cavity and lingual mucous membrane. The doctor was informed that the patient had the experience of oral ulcer 16 months ago by inquiring medical history. She received metronidazole for 3 days because of endodontitis, and then developed the oral ulcer. She was diagnosed as oral cavity and lingual mucous membrane ulcer induced by metronidazole. Metronidazole and cefuroxie axetil were stopped. She received the treatments with vitamin B complex tablet orally and topical application of oral ulcer paste. One week later, the ulcer was healed mainly. Key words: Metronidazole; Ulcer

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