Abstract
Clinical case: Female, 81years, with history of extensive ischemic stroke, epilepsy and dementia. Treated with phenytoin and warfarin beginning 7days before pulmonary thromboembolism. Refers to the ER with fever and altered mental status. The patient found himself with prostrate and temporo-spatial disorientation. The objective examination showed a 38°C temperature and skin with erythematous and necrotic areas. Complementary tests showed leukocytosis with neutrophilia and INR of 12.9. Admitted to the medical service and sought cooperation of Dermatology who described multiple cutaneous and subcutaneous board with extensive inflammatory and left thigh with areas of necrosis with exudative skin detachment — compatible with cutaneous necrosis secondary to warfarin.
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