Severe Sepsis Caused by California Serogroup Orthobunyavirus.

Daniel K Rogstad,David Neitzel,Larry M Baddour,Elizabeth Schiffman

doi:10.3201/eid2110.150394

Abstract

Severe Sepsis Caused by California Serogroup Orthobunyavirus.

Highlights

To the Editor: The California serogroup (CAL) of orthobunyaviruses, including Jamestown Canyon virus (JCV) and La Crosse virus (LACV), can cause neuroinvasive disease in humans [1,2,3]
The first human case of JCV disease in Minnesota, USA, was reported in 2013 [7], serologic evidence of the virus had been previously documented in the white-tailed deer population [8]
We report a case of severe sepsis in an adult with antibodies against CAL and suspected JCV disease

Summary

Introduction

To the Editor: The California serogroup (CAL) of orthobunyaviruses, including Jamestown Canyon virus (JCV) and La Crosse virus (LACV), can cause neuroinvasive disease in humans [1,2,3]. The first human case of JCV disease in Minnesota, USA, was reported in 2013 [7], serologic evidence of the virus had been previously documented in the white-tailed deer population [8]. Of the 22 human cases reported to the Centers for Disease Control and Prevention in the United States during 2013, 15 were neuroinvasive [7]. Given the lack of widespread testing availability and the few reported cases, the actual clinical spectrum of JCV infection, unlike that of LACV, remains unclear.

Results

Conclusion