Abstract
A cohort of seven infants (aged ≤1 year) with severe Kawasaki-like disease were diagnosed and treated at five hospitals in the UK between February and March, 2020 (appendix p 1). All of the infants received prompt intravenous immunoglobulins and steroid treatment, but none responded and all required the addition of a biological agent because of continued inflammation, recurring fever, and progressive changes on echocardiography. Six patients (86%) developed coronary artery aneurisms (Z score >2·5) and one infant died as a result of a ruptured aneurysm, despite early aggressive treatment.
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