Severe Invasive Group A Streptococcal Disease with Rhabdomyolysis but without Evidence of Shock or Local Myositis

Arthur Okere,David Schwartz,Patrick Schlievert,Randa Hamadeh,Philip Tierno

doi:10.3814/2009/786451

Abstract

We report a presentation in an adult with <i>Streptococcus pyogenes</i> bacteremia and invasive tissue disease with rhabdomyolysis, but without evidence of toxic shock syndrome or local myonecrosis. We thus investigated how this infecting strain differed from strains known to cause toxic shock syndrome.

Highlights

Severe invasive group A streptococcal infections have been previously described to cause bacteremia, necrotizing fasciitis, gangrenous myositis, pneumonia, or other possible syndromes associated with this organism being isolated from a usually sterile area of the body [1]
We report a presentation in an adult with Streptococcus pyogenes bacteremia and invasive tissue disease with rhabdomyolysis, but without evidence of toxic shock syndrome or local myonecrosis
We report a presentation in an adult with group A streptococcal bacteremia and other manifestations of toxic shock syndrome, not found to have the associated shock

Summary

Introduction

Severe invasive group A streptococcal infections have been previously described to cause bacteremia, necrotizing fasciitis, gangrenous myositis, pneumonia, or other possible syndromes associated with this organism being isolated from a usually sterile area of the body [1]. We report a presentation in an adult with Streptococcus pyogenes bacteremia and invasive tissue disease with rhabdomyolysis, but without evidence of toxic shock syndrome or local myonecrosis.

Results

Conclusion