Abstract
Group B Streptococci (GBS) and Escherichia coli are bacteria linked to preterm birth, stillbirth and neonatal sepsis. The impact of a severe bacterial infection on the transcriptional and immune response of placental chorionic villi is unknown, but may predispose to abruption and adverse neonatal outcomes. The study objective was to investigate early transcriptional responses, pathways and gene networks within placental chorionic villi after an experimental severe GBS or E. coli infection.
Published Version
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