Abstract
We report a case series of severe human bocavirus–associated pneumonia in adults in Seoul, South Korea. The virus accounted for 0.5% of all severe pneumonia cases. Structural lung disease and hematologic malignancy were common underlying diseases. Overall death rate was 54.5%. Higher death rates were associated with co-infection (83.3%) and immunocompromise (80.0%).
Highlights
We report a case series of severe human bocavirus–associated pneumonia in adults in Seoul, South Korea
We initially included all adult patients admitted to the intensive-care unit (ICU) with a diagnosis of pneumonia but later excluded patients with nonsevere pneumonia
2,519 adult patients were admitted to the ICU with the diagnosis of severe pneumonia
Summary
We report a case series of severe human bocavirus–associated pneumonia in adults in Seoul, South Korea. 2,519 adult patients were admitted to the ICU with the diagnosis of severe pneumonia. Among these 2,221 severe pneumonia patients, septic shock occurred in 1,306 (58.8%), and 2,141 (96.4%) required mechanical ventilation. Structural lung disease (26.9%) was the most common underlying disease in patients with CAP, and hematologic malignancy (25.4%) was the most common in patients with HAP (Appendix Table 1).
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