Severe feeding difficulties in 3C syndrome

Abstract

We describe a further patient with cranio-cerebellar-cardiac or 3C syndrome. She presented with the characteristic features of Dandy-Walker malformation of the brain, congenital cardiac defect, dysmorphic facies and post-natal growth failure. She had gastro-oesophageal reflux and severe feeding difficulties which are still present at the age of four years. Despite her numerous medical problems, she is demonstrating near-normal development. Feeding difficulties appear to be a prominent feature of the 3C syndrome.