Abstract
Purpose:Latanoprost is known to have several ocular side effects, including redness of the eyelids, lengthening of the eyelashes, an increase in iris pigmentation, and dryness of the eyes that causes discomfort. There are also several rarer systemic side effects reported in the literature, including chest pain.Case Report:Here we report a rare case of a patient who developed a cutaneous blistering rash on both eyelids, both sides of the neck, and the dorsum of both hands after direct contact with latanoprost eye drops. The lesions cleared following withdrawal of the eye drops.Conclusion:Topical latanoprost can cause severe blistering of the skin that could undermine a patient's confidence in the treating medical team. Reporting of an adverse effect is difficult when a generic topical medication is used.
Highlights
It is estimated that 500,000 individuals in the UK have glaucoma, and this figure does not include those who have yet to be diagnosed.[1]
We report a rare case of a severe cutaneous reaction to latanoprost eye drops
The authors subsequently contacted the patient via telephone. She informed us that the cutaneous lesions resolved following cessation of the offending latanoprost eye drops and that she remains very well. This is the first reported case of a blistering cutaneous rash secondary to use of latanoprost eye drops
Summary
It is estimated that 500,000 individuals in the UK have glaucoma, and this figure does not include those who have yet to be diagnosed.[1]. The patient had been monitored regularly for 3 years as a glaucoma suspect and at her last appointment had been diagnosed with normal-tension glaucoma At that time, her best-corrected vision was 6/24 in the right eye and 6/18 in the left eye. At the follow-up appointment, the patient informed us that she had stopped using the drops a month earlier when she developed a blistering rash around both eyes and on her hands She reported that the pain was so severe initially that she had been unable to sleep. The authors subsequently contacted the patient via telephone She informed us that the cutaneous lesions resolved following cessation of the offending latanoprost eye drops and that she remains very well
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