Severe COVID-19 Pneumonia in Parkinson’s Disease with Mental Retardation and Wavy Triple Sign (Yasser’s Sign)-Bad Association with Good Outcome

Abstract

Rationale: Parkinson’s disease is a degenerative neurological disorder accompanied by motor symptoms such as slow movement, tremors, rigidity, and imbalance. PD may be complicated by cognitive impairment, mental disorders, sleep disorders, pain, and sensory disturbances. Despite the quickly swept of COVID-19 across the globe, several studies have a lack of scientific accuracy in the Parkinson’s disease literature that is not immune in origin. Some symptoms of parkinsonism have been reported following COVID-19. The Wavy triple electrocardiographic sign (Yasser’s sign) is an innovative diagnostic sign in hypocalcemia. Patient Concerns: A 35-year-old single, mentally retarded, Egyptian, a female patient was presented to the physician outpatient clinic (POC) with pneumonia and Parkinson’s disease. Diagnosis: Severe COVID-19 pneumonia in Parkinson’s disease with mental retardation and Wavy triple sign (Yasser’s sign). Interventions: Electrocardiography, chest CT scan, oxygenation, and arterial blood gas. Outcomes: Electrocardiographic, radiographic, and clinical stabilization was the result. Lessons: The association of COVID-19 pneumonia in Parkinson’s disease with mental retardation and the Wavy triple sign (Yasser’s sign) is interesting and stupendous. The constellation of hypotension, ECG sinus tachycardia, hypoxia, Wavy triple sign (Yasser’s sign) of hypocalcemia, elevated creatinine, elevated urea, elevated liver enzymes, and marked elevated d-dimer in the presence of severe bilateral COVID-19 pneumonia may carry a poor prognostic outcome and is indicating a high-risk condition.