Abstract
5 month old female baby presented with cough followed by respiratory distress and not gaining weight. There was no history of fever, diarrhea or recurrent infections. Her elder brother died due to respiratory illness at the age of 8 months. There was accelerated reaction at BCG site. Repeated peripheral blood examination showed absolute lymphopenia. Thymus shadow was absent in X-ray. Patient was evaluated and diagnosed as Severe combined immune deficiency (T-, B+, NK-).
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