Abstract
To report a case of postnatal, postoperative amiodarone-induced hypothyroidism in an infant with a congenital heart defect. Case report and literature review. Pediatric intensive care unit at a freestanding tertiary care children's hospital. At 7 wks of age, a female infant with a congenital heart defect was confirmed to have profound hypothyroidism after amiodarone administration for a postoperative cardiac arrhythmia. Levothyroxine treatment. Thyroid function tests were regularly performed to guide levothyroxine dosing. Thyroid hormone replacement was discontinued after the infant had been off amiodarone for 6 mos. Given the potential adverse developmental consequences associated with hypothyroidism during infancy and early childhood, thyroid function tests should be carefully monitored in any infant treated with amiodarone.
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