Abstract
Objective A group of 148 peach allergic patients, recruited in a ongoing clinical study (Clinical Trials.gov, protocol ID NCT00715156) aimed at studying the relationship between the clinical manifestations to peach and the positivity to different peach major allergens (Pru p 3, 1 and 4), were divided into 2 groups according to peach induced symptoms: group A (mild-OAS; 76 pts) and group B (severe-OAS with systemic symptoms, 72 pts). These patients were examined to see if severe allergic symptoms to peach were a risk factor for developing severe symptoms to other plant foods allergens.
Highlights
The hypersensitivity reactions to plant-food allergens may consist of oral allergic symptoms (OAS) only or OAS plus systemic symptoms up to anaphylaxis
A group of 148 peach allergic patients, recruited in a ongoing clinical study (Clinical Trials.gov, protocol ID NCT00715156) aimed at studying the relationship between the clinical manifestations to peach and the positivity to different peach major allergens (Pru p 3, 1 and 4), were divided into 2 groups according to peach induced symptoms: group A and group B. These patients were examined to see if severe allergic symptoms to peach were a risk factor for developing severe symptoms to other plant foods allergens
We investigated the type of reaction to peach and to other foods by means of a clinical questionnaire and confirmed their allergy with open food challenge or double blind challenge and, when necessary, double blind challenge + exercise
Summary
The hypersensitivity reactions to plant-food allergens may consist of oral allergic symptoms (OAS) only or OAS plus systemic symptoms up to anaphylaxis. There is great interest in evaluating the risk factors for developing the more severe and systemic reactions
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