Abstract

Effective systemic treatments for severe acne vulgaris, such as oral antibiotics, oral isotretinoin and anti-andro-gens, are often associated with undesirable side-effects or are limited to a selected patient population. Furthermore, some patients with severe acne fail to respond to these therapies (1).Etanercept, a dimeric fusion protein linking part of the human p75 tumour necrosis factor (TNF) receptor extracellular domain with the Fc region of IgG

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