Severe Acne Successfully Treated With Etanercept

Abstract

Effective systemic treatments for severe acne vulgaris, such as oral antibiotics, oral isotretinoin and anti-andro-gens, are often associated with undesirable side-effects or are limited to a selected patient population. Furthermore, some patients with severe acne fail to respond to these therapies (1).Etanercept, a dimeric fusion protein linking part of the human p75 tumour necrosis factor (TNF) receptor extracellular domain with the Fc region of IgG