Abstract
1. What are this patient’s most striking clinical and laboratory findings? 2. How do you explain this patient’s most striking clinical and laboratory findings? 3. What is this patient’s most likely diagnosis? 4. What factors predispose patients to 5-fluorouracil (5-FU) toxicity? 5. What is the clinical utility of evaluating a patient for dihydropyrimidine dehydrogenase (DPD) deficiency? 6. What laboratory tests can be used to detect DPD deficiency? 7. What are the therapeutic options for this patient?
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