Abstract

An 18-year-old male was clinically diagnosed as having choroidal osteoma in August 2005. Ocular examination revealed 4 disk diameter orange colored elevated lesion in the left eye. Ultrasonography and computed tomographic (CT) scan of orbit, fluorescein angiogram (FA) and optical coherence tomography (OCT) confirmed the diagnosis of choroidal osteoma. The patient was followed up at regular intervals and on the 4th year followup developed a choroidal neovascular membrane (CNVM) within the osteoma. It was treated with intravitreal bevacizumab. Patient was stable for next 2 years followed by a recurrence of the membrane for which further injections were given to regress it. During this period there was consistent progression of the size of osteoma as well as its decalcified component. We documented progression of the osteoma along with regression of the CNVM with color photo and OCT for 7 years. Spectral domain features of the osteoma were noted in relation to changes occurring in its decalcified area. Long-term follow-up suggests that choroidal osteoma along with the decalcification part within it progresses with time. Intravitreal bevacizumab is effective in treating the CNVM secondary to choroidal osteoma.

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