Seven New Norditerpenoid Alkaloids from Spanish Consolida orientalis

Abstract

AbstractSeven new norditerpenoid alkaloids named 1‐O‐demethyltricornine (1), 14‐O‐benzoyltakaosamine (2), 1‐O,19‐didehydrotakaosamine (3), 14‐O‐demethyldelboxine (4), all belonging to the lycoctonine‐type alkaloids, and 8‐O‐methylconsolarine (5), 14‐O‐deacetylpubescenine (6), and 18‐O‐benzoyl‐14‐O‐deacetyl‐18‐O‐demethylpubescenine (7), these belonging to the rare group of the 6‐epilycoctonine‐type alkaloids, were isolated from the aerial parts of Consolida orientalis (Gay) Schröd. The structures of the new compounds were elucidated by 1D‐ and 2D‐NMR and HR‐EI‐MS. Moreover, 37 known norditerpenoid alkaloids (lycoctonine‐type) were isolated and identified by comparing their spectral data with those reported in the literature.