Abstract
Abstract A simple qualitative procedure is outlined for the conformational analysis of cycloheptane derivatives with particular attention to the natural perhydroazulenes. The procedure allows discrimination amongst different configuration and conformational isomers on grounds of thermodynamic stability. Using this procedure it is possible, by analyzing the known reactions of each, to derive stereochemical structures for the sesquiterpenes lactucin, artabsin and arborescin, tenulin, balduilin, and helenalin.
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