Abstract
Five sesquiterpene lactones, 8-acetylarteminolide ( 1), artanomaloide ( 2), arteminones ( 3 and 4), and dehydromatricarin ( 5), were isolated from the methanolic extract of the flower of Artemisia sylvatica and characterized on the basis of their spectral data. New sesquiterpene lactone 1 was identified as a configurational isomer of artanomaloide ( 2), and the new arteminones 3 and 4 are determined as stereoisomers. 8-Acetylarteminolide ( 1) strongly inhibited FPTase with an IC 50 of 1.8 μM, however, the other sesquiterpene lactones mildly inhibited the transferase with an IC 50 of 22–300 μM.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
