Abstract

Five known guaianolides were isolated from the areal part of Saussurea lipshitzii(Asteraceae) collected in South Gobi, Mongolia: cynaropicrin (I), janerin (II), chlorojanerin (III), 15-deschloro-15-acetoxychlorojanerin (IV), and 15-deschloro-15-hydroxychlorojanerin (V). The correlation between I-V and the β-configuration of the C-4/C-15 bond in II-V was shown by biomimetic chemical transformations, suggesting compound I as the possible common precursor. (

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