Abstract
The flower heads of Achillea collina afforded 31 individual sesquiterpene lactones, among which nine guaianolides ( 1, 16, 20, 21, 23, 27– 30), a germacranolide ( 18) and a dimeric guaianolide ( 31) were found to be new natural products. The lactones 2– 4, 12, 14, 15, 17, 19 and 25 were isolated for the first time from the investigated species. Their structures were established by spectral methods.
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