Abstract
The genus Schkuhria is known as a source of sesquiterpene lactones of different skeletons, some of which display cytotoxic activity [1]. Due to botanical revision, some Schkuhria species from North America (i.e.: S. anthemoidea, S. virgata) have been reclassified and identified as S. pinnata var. wislizeni [2]. Our current investigation on the aerial parts of this species led to the isolation of the sesquiterpene lactones 1–3 and the phenyl propanoids 4 and 5. 2 represents a Diels Alder adduct derived from a guaia-1(2),4(5)-dienolide as diene and the 11,13-olefin of 1 as dienophile, and the theoretical study of the reactants predicted the product. The spectroscopic analysis of 3 allowed the structural reassignment of a compound previously isolated from S. anthemoidea [3]. The antioxidant assay using a rat pancreas homogenate model indicated that 4 and 5 displayed activity and also DPPH radical scavenger capacity. Acknowledgement: To Direccion General de Asuntos de Personal Academico, UNAM, Chavez M.I., Cogordan J.A., Velasco L., Patino R. (Instituto de Quimica, UNAM).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
