Sesquiterpene lactone glucosides and alkyl glycosides from the fruit of cumin

Abstract

From the polar portion of the methanolic extract of cumin (fruit of Cuminum cyminum L.), two sesquiterpenoid glucosides, cuminoside A and B, and two alkyl glycosides were isolated together with five known compounds. Their structures were established as (1 S,5 S,6 S,10 S)-10-hydroxyguaia-3,7(11)-dien-12,6-olide β- d-glucopyranoside, (1 R,5 R,6 S,7 S,9 S,10 R,11 R)-1,9-dihydroxyeudesm-3-en-12,6-olide 9- O-β- d-glucopyranoside, methyl β- d-apiofuranosyl-(1→6)-β- d-glucopyranoside and ethane-1,2-diol 1- O-β- d-apiofuranosyl-(1→6)-β- d-glucopyranoside, respectively.