Abstract
Background:- Achyranthes aspera L. (Amaranthaceae) locally known as “Telenge or ambulale” (Amharic) and Muchele (Tigrigna)” is one of the traditional medicinal plant used as contraceptive, for relieving asthma and cough, and anti snake bite in the indigenous health care delivery system of Ethiopia Objective:- Identifying and characterization of the chemical constituents of elucidations of the n-buthanol fractions of the methanolic leaves extracts of Achyranthes aspera Method:- Structural elucidations of the compounds was based on IR, UV, 1 D NMR ( 1 H, 13 C &DEPT) and 2 D NMR (COSY, HMQC &HMBC) spectroscopic techniques. Result: Phytochemical investigation of the leaves of this plant resulted in the isolation and characterization of two compounds AA-1 and AA-2 . Compound AA-1 is sesquiterpene named as 4,4a,7,8-tetrahydro-4-hydroxy-4a,7,8-trimethyl-8-(tetrahydro-3,4,5-trihydroxy-6-(hydroxymethyl)-2H-pyran-2-yloxy) naphthalen-2(3H)-one. Compound AA-2 is an insect molting ecdysteroid hormone named as, 20-hydroxyecdysone. Conclusion: From this study, two compounds were isolated and structurally identified. Compound AA-1 is the first report from A. aspera and plants belonging to the same species and family. While compound AA-2 was reported previously from the same plant. Keywords : Achyrannthes aspera, sesquiterpene, ecdysteroid, structural elucidation DOI : 10.7176/CER/11-3-02 Publication date : April 30 th 2019
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